Audlem is one of thirty-seven churches that make up the Cheshire South Circuit. The thirty-seven churches are grouped in thirteen 'Mission Areas', with Audlem being in the Audlem Mission Area along with the Methodist Church in Hankelow.

Four previous circuits (Crewe, Nantwich, Sandbach & Alsager, Whitchurch) came together in September 2010 to form the Cheshire South Circuit. It is currently the largest circuit in the Chester & Stoke-on-Trent District, with more than seventeen hundred members. The Circuit employs a large team of both presbyters and lay people and is led by Co-Superintendents Malcolm Lorimer and Michael Parrott.